单细胞与空转测序相关文章
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当前共找到 41633 篇文献，本页显示第 101 - 120 篇。
| 序号 | 推送日期 | 文章 | 类型 | 简述 | 创新点 | 不足 | 研究目的 | 研究对象 | 领域 | 病种 | 技术 | 模型 | 数据类型 | 样本量 | 平台公司 | 平台技术 | 具体产品 | 平台详情 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 101 | 2026-07-25 |
The IRE1-XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5-HT Dependent Endogenous Anti-Autophagy Mechanism
2026-Jul-23, Advanced science (Weinheim, Baden-Wurttemberg, Germany)
DOI:10.1002/advs.76755
PMID:42490691
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 102 | 2026-07-25 |
Integrative single-cell and machine learning analysis identifies a tumor doubling time-related prognostic signature and therapeutic targets in head and neck squamous cell carcinoma
2026-Jul-23, Translational oncology
IF:4.5Q1
DOI:10.1016/j.tranon.2026.102927
PMID:42492364
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 103 | 2026-07-25 |
Single-cell and spatial transcriptomics reveal SUV39H1 as a master epigenetic driver of immunosuppressive niche and stemness in bladder cancer
2026-Jul-23, Translational oncology
IF:4.5Q1
DOI:10.1016/j.tranon.2026.102929
PMID:42492366
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 104 | 2026-07-25 |
Brain corticogenesis promotes SARS-CoV-2 neuro-glial tropism through lipid-dependent viral replication
2026-Jul-23, Stem cell reports
IF:5.9Q2
DOI:10.1016/j.stemcr.2026.103020
PMID:42492515
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 105 | 2026-07-25 |
High and intermittent hydrostatic pressure promotes maturation of engineered cardiac tissues derived from human pluripotent stem cells
2026-Jul-23, Stem cell reports
IF:5.9Q2
DOI:10.1016/j.stemcr.2026.103019
PMID:42492513
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 106 | 2026-07-25 |
Tissue-reactive zonation of mesenchymal-like phenotypes in human glioblastoma
2026-Jul-23, Med (New York, N.Y.)
DOI:10.1016/j.medj.2026.101228
PMID:42492522
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 107 | 2026-07-25 |
Xist-mediated B cell modulation: Implications for immune dysregulation in T1DM
2026-Jul-23, Biochimica et biophysica acta. Molecular basis of disease
DOI:10.1016/j.bbadis.2026.168376
PMID:42492838
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 108 | 2026-07-25 |
Single-cell RNA sequencing reveals intrinsic and microbiota-associated sex differences in murine lung
2026-Jul-23, Mucosal immunology
IF:7.9Q1
DOI:10.1016/j.mucimm.2026.100389
PMID:42492858
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 109 | 2026-07-25 |
A vesicular trafficking pathway mediated by N-ethylmaleimide-sensitive factor governs integrin maturation and podocyte integrity
2026-Jul-23, Kidney international
IF:14.8Q1
DOI:10.1016/j.kint.2026.06.035
PMID:42492856
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 110 | 2026-07-25 |
CNS immune remodelling in SLE associated with anti-CD19 CAR-T therapy
2026-Jul-23, Annals of the rheumatic diseases
IF:20.3Q1
DOI:10.1016/j.ard.2026.06.030
PMID:42493310
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 111 | 2026-07-25 |
Spatial transcriptomics reveals mechanism of autoimmunity driven by internalised autoantibodies
2026-Jul-23, Annals of the rheumatic diseases
IF:20.3Q1
DOI:10.1016/j.ard.2026.06.028
PMID:42493309
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 112 | 2026-07-25 |
Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance
2026-Jul-23, Immunology
IF:4.9Q2
DOI:10.1111/imm.70176
PMID:42493359
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 113 | 2026-07-25 |
Focal astrocyte loss reveals nuclear translocation during lesion repopulation
2026-Jul-23, Nature neuroscience
IF:21.2Q1
DOI:10.1038/s41593-026-02354-5
PMID:42493549
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 114 | 2026-07-25 |
The ubiquitination of CD274 at MERCs enhances the anti-tumor immunity of cervical cancer
2026-Jul-23, Autophagy
IF:14.6Q1
DOI:10.1080/15548627.2026.2708579
PMID:42494073
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 115 | 2026-07-25 |
SpatialFlux: An R package for distance gradient analysis in spatial transcriptomics
2026-Jul-23, Bioinformatics (Oxford, England)
DOI:10.1093/bioinformatics/btag543
PMID:42494106
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 116 | 2026-06-06 |
Neural crest cell signatures drive tumorigenesis in tuberous sclerosis complex and lymphangioleiomyomatosis
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.195013
PMID:42241577
|
研究论文 | 通过单细胞RNA测序揭示TSC和LAM肿瘤来源于神经嵴细胞，并鉴定出新的生物标志物 | 首次提出TSC和LAM的神经嵴病理模型，发现肿瘤细胞亚群表达颅神经嵴基因特征，并鉴定SPP1、LCN2和KRT18等新型生物标志物 | 主要基于小鼠模型和有限的患者样本，Tsc2 KO对趋化性影响较小，需进一步验证生物标志物在更大临床队列中的价值 | 阐明TSC和LAM的细胞起源及其肿瘤发生机制 | Tsc2+/-小鼠肾囊腺瘤细胞、LAM患者病灶和血清样本 | 数字病理学 | 结节性硬化症、淋巴管平滑肌瘤病 | scRNA-seq | NA | 基因表达数据 | Tsc2+/-小鼠肾囊腺瘤样本及LAM患者病灶和血清 | NA | 单细胞RNA测序 | NA | NA |
| 117 | 2026-07-25 |
Not all reference samples are equal in single-cell transcriptomics of human kidney tissue
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.204385
PMID:42160485
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 118 | 2026-07-25 |
p21-senescent cells drive pancreatic islet dysfunction through targetable paracrine signaling in type 2 diabetes
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.197310
PMID:42262869
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 119 | 2026-07-25 |
A loss-of-function polymorphism in the propeptide of lysyl oxidase exacerbates atherosclerosis
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.201535
PMID:42484377
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 120 | 2026-07-25 |
GZMK-expressing tissue-resident memory CD8+ T cells participate in human intestinal acute graft-versus-host disease
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.199156
PMID:42484374
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |