单细胞与空转测序相关文章
本数据库通过收集和整理最新科研文献信息而得，供了解领域前沿进展之用。数据源自 PubMed Data ，每日自动更新（使用关键词“['single-cell sequencing', 'single-cell RNA sequencing', 'single-cell transcriptomics', 'single-cell RNA-seq', 'single-cell transcriptome', 'scRNA-seq', 'spatial transcriptomics']”过滤），已收录文献数量参见 统计表格。表格内容由 GPT 自动整理，可能存在错误或遗漏，请使用时务必注意核实！
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当前共找到 814 篇文献，本页显示第 541 - 560 篇。
| 序号 | 推送日期 | 文章 | 类型 | 简述 | 创新点 | 不足 | 研究目的 | 研究对象 | 领域 | 病种 | 技术 | 模型 | 数据类型 | 样本量 | 平台公司 | 平台技术 | 具体产品 | 平台详情 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 541 | 2026-07-25 |
Single-cell resolution of skeletal muscle aging: Current paradigms and perspectives
2026-Jul-23, Ageing research reviews
IF:12.5Q1
DOI:10.1016/j.arr.2026.103272
PMID:42492807
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 542 | 2026-07-25 |
Developing an epithelial signature for prognosis of papillary thyroid carcinoma
2026-Jul-01, Endocrine-related cancer
IF:4.1Q2
DOI:10.1530/ERC-25-0515
PMID:42447050
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 543 | 2026-07-25 |
Single-Cell Profiling Reveals Stromal-Immune Remodeling in HNSCC After TPF-Based Neoadjuvant Chemotherapy
2026-Jul-24, Head & neck
DOI:10.1002/hed.70408
PMID:42495797
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 544 | 2026-07-25 |
Continuous modeling of primate embryogenesis from totipotency to early organogenesis
2026-Jul-23, Cell
IF:45.5Q1
DOI:10.1016/j.cell.2026.05.023
PMID:42269606
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 545 | 2026-07-25 |
Rapid recovery and functional resilience of bone marrow function post B-cell acute lymphoblastic leukemia
2026-07-23, Haematologica
IF:8.2Q1
DOI:10.3324/haematol.2025.300439
PMID:42489070
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 546 | 2026-07-25 |
The transcriptional landscape in thyroid cancer: current status of circulating biomarkers and liquid biopsy approaches
2026-Jul-23, Expert review of anticancer therapy
IF:2.9Q2
DOI:10.1080/14737140.2026.2708770
PMID:42490163
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 547 | 2026-07-25 |
CNS immune remodelling in SLE associated with anti-CD19 CAR-T therapy
2026-Jul-23, Annals of the rheumatic diseases
IF:20.3Q1
DOI:10.1016/j.ard.2026.06.030
PMID:42493310
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 548 | 2026-07-25 |
Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance
2026-Jul-23, Immunology
IF:4.9Q2
DOI:10.1111/imm.70176
PMID:42493359
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 549 | 2026-07-25 |
Focal astrocyte loss reveals nuclear translocation during lesion repopulation
2026-Jul-23, Nature neuroscience
IF:21.2Q1
DOI:10.1038/s41593-026-02354-5
PMID:42493549
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 550 | 2026-07-25 |
A loss-of-function polymorphism in the propeptide of lysyl oxidase exacerbates atherosclerosis
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.201535
PMID:42484377
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 551 | 2026-07-25 |
GZMK-expressing tissue-resident memory CD8+ T cells participate in human intestinal acute graft-versus-host disease
2026-Jul-22, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.199156
PMID:42484374
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 552 | 2026-07-25 |
SC-framework: A robust and FAIR semi-interactive environment for single-cell resolution datasets
2026-Jul-17, iScience
IF:4.6Q1
DOI:10.1016/j.isci.2026.116631
PMID:42491580
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 553 | 2026-07-25 |
Generation of a distal lung cancer organoid model using oncogenic ret-expressing induced pluripotent stem cells
2026-Jul-17, iScience
IF:4.6Q1
DOI:10.1016/j.isci.2026.116554
PMID:42491694
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 554 | 2026-07-25 |
Immune-epithelial crosstalk governs immune checkpoint inhibitor efficacy in colorectal cancer
2026-Jul-17, iScience
IF:4.6Q1
DOI:10.1016/j.isci.2026.116544
PMID:42491875
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 555 | 2026-07-25 |
Integrated single-cell and network analysis identifies SLAMF7 as a secretory mediator of the joint-lung axis in rheumatoid arthritis-associated interstitial lung disease targetable by Tanshinone IIA
2026-Jul-15, Phytomedicine : international journal of phytotherapy and phytopharmacology
IF:6.7Q1
DOI:10.1016/j.phymed.2026.158583
PMID:42492262
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 556 | 2026-07-25 |
Tooth development, replacement and regeneration
2026-Jul-15, Development (Cambridge, England)
DOI:10.1242/dev.205531
PMID:42496585
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 557 | 2026-07-25 |
Single-cell transcriptomics identifies CD36 as a negative regulator of osteogenic differentiation in murine osteoporosis
2026-Jul-07, Joint bone spine
IF:3.8Q1
DOI:10.1016/j.jbspin.2026.106096
PMID:42413604
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 558 | 2026-07-25 |
E2F1 Drives Endothelial Arterial Programming in Pulmonary Arterial Hypertension
2026-Jul-07, bioRxiv : the preprint server for biology
DOI:10.64898/2026.07.02.736230
PMID:42465492
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 559 | 2026-04-30 |
Integration of Spatiotemporal Multi-Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome-Mediated Stress Adaptation
2026-Jul, Advanced science (Weinheim, Baden-Wurttemberg, Germany)
DOI:10.1002/advs.202520438
PMID:42037236
|
研究论文 | 整合空间转录组学与质谱成像技术构建桃果实早期发育的多维图谱，揭示代谢区室化与毛状体介导的抗逆遗传基础 | 首次构建蔷薇科水果的空间分辨多组学资源，并鉴定出Prupe.7G196500为整合茉莉酸信号促进毛状体发育与抗旱性的新型候选调控因子 | 对早期器官发生的系统层面理解仍有限，且研究仅针对单一物种及其变种 | 研究桃果实早期发育过程中基因表达与代谢的时空协调机制及其遗传基础 | 桃果实及其光滑变种油桃 | 数字病理学 | NA | 空间转录组学, 质谱成像 | NA | 基因表达数据, 代谢物数据 | NA | NA | 空间转录组学, 质谱成像 | NA | NA |
| 560 | 2026-04-30 |
Network medicine and single-cell mapping identify a collagen-rich, fibrosis-associated hub module in Duchenne muscular dystrophy
2026-Jul, Naunyn-Schmiedeberg's archives of pharmacology
DOI:10.1007/s00210-026-05376-9
PMID:42053795
|
研究论文 | 通过网络医学和单细胞映射识别杜氏肌营养不良症中胶原丰富、与纤维化相关的枢纽模块 | 首次通过加权基因共表达网络分析和单细胞RNA测序，将杜氏肌营养不良症的纤维化信号特异性地映射到肌腱成纤维细胞，并鉴定了六个关键枢纽基因，同时筛选出候选药物卤夫酮 | 尚不清楚，摘要中未明确提及局限性 | 识别与杜氏肌营养不良症细胞外基质重塑相关的关键转录程序、枢纽基因网络、免疫微环境特征，并预测潜在治疗药物 | 杜氏肌营养不良症患者的转录组数据和单细胞RNA测序数据，以及体外炎症诱导的成纤维细胞模型 | 生物信息学 | 杜氏肌营养不良症 | 加权基因共表达网络分析、单细胞RNA测序、体外验证 | NA | 转录组数据、单细胞RNA测序数据 | NA | NA | 单细胞RNA测序 | NA | NA |