单细胞与空转测序相关文章
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当前共找到 467 篇文献，本页显示第 21 - 40 篇。
| 序号 | 推送日期 | 文章 | 类型 | 简述 | 创新点 | 不足 | 研究目的 | 研究对象 | 领域 | 病种 | 技术 | 模型 | 数据类型 | 样本量 | 平台公司 | 平台技术 | 具体产品 | 平台详情 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21 | 2026-07-26 |
PFOA promotes PMAIP1-MCL1 apoptotic vulnerability within a BHLHE41-associated macrophage regulatory architecture in atherosclerosis
2026-Jul-22, Chemico-biological interactions
IF:4.7Q1
DOI:10.1016/j.cbi.2026.112265
PMID:42486287
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 22 | 2026-07-26 |
Robust and generalizable CNV detection for single-cell sequencing assays
2026-Jul-17, Nucleic acids research
IF:16.6Q1
DOI:10.1093/nar/gkag636
PMID:42500822
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 23 | 2026-05-08 |
Predictive control of human pancreatic cell fate using a digital model of in vitro differentiation
2026-Jul-16, bioRxiv : the preprint server for biology
DOI:10.64898/2026.04.27.721124
PMID:42094425
|
研究论文 | 构建胰腺胰岛分化的数字孪生模型以预测细胞命运 | 首次整合时间序列多组学数据构建预测性数字孪生模型，能够解析谱系轨迹并推断细胞命运决定的因果调控因子 | 未提及具体局限性 | 建立预测性框架以解析细胞命运特化和谱系轨迹的调控决定因素 | 人诱导多能干细胞分化为胰腺胰岛类器官的过程 | 机器学习 | 糖尿病 | 单细胞测序 | 数字孪生模型 | 时间序列多组学数据 | NA | NA | 单细胞多组学 | NA | NA |
| 24 | 2026-07-15 |
The perineurium integrates leptin with its sympathetic outflow to protect against obesity
2026-Jul, Nature metabolism
IF:18.9Q1
DOI:10.1038/s42255-026-01555-3
PMID:42443582
|
研究论文 | 使用小鼠交感神经节的单细胞RNA测序，发现神经束膜细胞整合瘦素与交感流出以抵抗肥胖，揭示了瘦素作用中外周调控的新机制 | 首次发现神经束膜细胞同时表达瘦素受体和β-肾上腺素能受体，并揭示其在调节能量消耗和体重中的关键作用 | 研究主要基于小鼠模型，临床观察仅为相关性分析，且未排除其他细胞类型在过程中的贡献 | 探究瘦素外周传入与交感神经传出平衡的调控机制 | 小鼠交感神经节的神经束膜细胞、脂肪组织中的交感神经元束 | 单细胞转录组学 | 肥胖 | 单细胞RNA测序 | NA | 单细胞转录组数据 | 小鼠交感神经节样本 | 10x Genomics | 单细胞RNA-seq | 10x Chromium | 10x Chromium Single Cell 3' |
| 25 | 2026-07-25 |
Developing an epithelial signature for prognosis of papillary thyroid carcinoma
2026-Jul-01, Endocrine-related cancer
IF:4.1Q2
DOI:10.1530/ERC-25-0515
PMID:42447050
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 26 | 2026-07-26 |
Integrated Proteogenomics and Single-Cell Transcriptomics Prioritize Putative Protective Plasma Proteins for Hidradenitis Suppurativa
2026-Jul, Experimental dermatology
IF:3.5Q1
DOI:10.1111/exd.70332
PMID:42499219
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 27 | 2026-07-25 |
Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina
2026-Jul-24, Science advances
IF:11.7Q1
DOI:10.1126/sciadv.adv9162
PMID:42490430
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 28 | 2026-07-25 |
Mechanisms and therapeutic targets in distant metastasis of lung adenocarcinoma
2026-Jul-24, Signal transduction and targeted therapy
IF:40.8Q1
DOI:10.1038/s41392-026-02817-y
PMID:42493498
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 29 | 2026-07-25 |
Single-Cell Profiling Reveals Stromal-Immune Remodeling in HNSCC After TPF-Based Neoadjuvant Chemotherapy
2026-Jul-24, Head & neck
DOI:10.1002/hed.70408
PMID:42495797
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 30 | 2026-07-25 |
Single-cell transcriptomics reveal PD-1-loss-driven immune dysregulation of pulmonary lymphocytes during early Mycobacterium tuberculosis infection
2026-Jul-24, Microbiology spectrum
IF:3.7Q2
DOI:10.1128/spectrum.01199-26
PMID:42496156
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 31 | 2026-07-25 |
Continuous modeling of primate embryogenesis from totipotency to early organogenesis
2026-Jul-23, Cell
IF:45.5Q1
DOI:10.1016/j.cell.2026.05.023
PMID:42269606
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 32 | 2026-07-25 |
Rapid recovery and functional resilience of bone marrow function post B-cell acute lymphoblastic leukemia
2026-07-23, Haematologica
IF:8.2Q1
DOI:10.3324/haematol.2025.300439
PMID:42489070
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 33 | 2026-07-25 |
Single-Cell RNA sequencing reveals clonally-expanded CD4+ tissue-resident memory T cells in Histidyl-tRNA Synthetase-induced myositis
2026-Jul-23, JCI insight
IF:6.3Q1
DOI:10.1172/jci.insight.208009
PMID:42490151
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 34 | 2026-07-25 |
The transcriptional landscape in thyroid cancer: current status of circulating biomarkers and liquid biopsy approaches
2026-Jul-23, Expert review of anticancer therapy
IF:2.9Q2
DOI:10.1080/14737140.2026.2708770
PMID:42490163
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 35 | 2026-07-25 |
PRISM: Prior-enhanced Inference for Spatial Transcriptomic Cell Type Mapping
2026-Jul-23, Bioinformatics (Oxford, England)
DOI:10.1093/bioinformatics/btag515
PMID:42490201
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 36 | 2026-07-25 |
One-carbon metabolism upregulated in lupus promotes the differentiation and effector functions of human B and T cells
2026-Jul-23, Rheumatology (Oxford, England)
DOI:10.1093/rheumatology/keag381
PMID:42490203
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 37 | 2026-07-25 |
Single-cell multiomics connects 3D genome and transcriptome alterations in Alzheimer's disease
2026-Jul-23, Science (New York, N.Y.)
DOI:10.1126/science.adz1652
PMID:42490473
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 38 | 2026-07-25 |
The IRE1-XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5-HT Dependent Endogenous Anti-Autophagy Mechanism
2026-Jul-23, Advanced science (Weinheim, Baden-Wurttemberg, Germany)
DOI:10.1002/advs.76755
PMID:42490691
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 39 | 2026-07-25 |
Integrative single-cell and machine learning analysis identifies a tumor doubling time-related prognostic signature and therapeutic targets in head and neck squamous cell carcinoma
2026-Jul-23, Translational oncology
IF:4.5Q1
DOI:10.1016/j.tranon.2026.102927
PMID:42492364
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 40 | 2026-07-25 |
Single-cell and spatial transcriptomics reveal SUV39H1 as a master epigenetic driver of immunosuppressive niche and stemness in bladder cancer
2026-Jul-23, Translational oncology
IF:4.5Q1
DOI:10.1016/j.tranon.2026.102929
PMID:42492366
|
NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |